Do you have depression?
Be part of a clinical trial investigating a treatment for major depressive disorder.
The purpose of this phase 2 clinical research study is to evaluate the safety and efficacy of an investigational medication for major depressive disorder (MDD).
Approximately 172 participants will be taking part in this study. We are looking for males and females, 18 to 64 years of age that are diagnosed with depression.
To find out if the study may be suitable for you, please click the "See if this trial is a match for you"-button.
The purpose of this study is to evaluate the benefit and safety of an investigational medication for treating major depressive disorder. This medication has been previously tested in three early phase trials (phase 1) and four efficacy studies (more about study phases here).
The participants of the study will continue on prescribed medication for depression alongside either the investigational medication or a placebo. A placebo is a treatment that looks and feels like the investigational medication but does not have any active ingredients or therapeutic effect. A placebo is used as a control to compare the effect of the investigational medication. The participants in this study have a 50% chance of receiving either the investigational medication or the placebo.
The total duration of the study is 16 weeks.
Major depressive disorder is also known as depression or clinical depression. The main symptom is a period of at least two weeks with persistent feelings of sadness or emptiness.
For more information about depression and other mood disorders see the information page.
We are looking for men and women, aged 18 to 64 years, who are diagnosed with depression. Please answer the study questions to see if you may pre-qualify by clicking on the "See if this trial is a match for you"-button.
There are other criteria that need to be fulfilled to be able to take part in the study. If you pre-qualify, you and the medical team at the study clinic will determine if this study is suitable for you.
Before the study begins, you will visit the clinic for screening where you will be asked to read the study information and sign an informed consent form before any study-required procedures are performed. Tests are performed to determine if you qualify to participate in the study.
During the study, you will visit the clinic periodically for study procedures and/or clinical evaluations and tests. There will be 11 scheduled visits during the entire study. It is voluntary to participate, and you can decide to stop at any time.
Study investigational medication, study-related procedures, and study visits will be provided at no cost. Study related travel expenses may be reimbursed.
For additional information about clinical trials in general please see the FAQ-page.
There is more information in the "For loved ones"-section about what you can do and how to support your loved one. If your loved one agrees, it can be a good idea to help them fill out the self-assessment if you think this study might be suitable for them.